Objective Evaluation Of Tendon Morphology By Ultrasonography In Treatment Of Recalcitrant Tennis Elbow By Autologous Platelet Rich Plasma

  • Jain S Department of Orthopaedics, Mahatma Gandhi Memorial Medical College & Maharaja Yashwantrao Hospital, Indore (M.P.), India.
  • Banodha L Department of Orthopaedics, Mahatma Gandhi Memorial Medical College & Maharaja Yashwantrao Hospital, Indore (M.P.), India
  • Kelkar R Department of Orthopaedics, Mahatma Gandhi Memorial Medical College & Maharaja Yashwantrao Hospital, Indore (M.P.), India
  • Gautam V Department of Orthopaedics, Mahatma Gandhi Memorial Medical College & Maharaja Yashwantrao Hospital, Indore (M.P.), India
Keywords: Tennis elbow, Platelet rich plasma, Ultrasonography

Abstract

Background: Traditional therapies of tennis elbow have shown inconsistent outcomes as they do not deal with poor tendon healing properties secondary to poor vascularization. Local platelet rich plasma injections, which provide locally high concentration of growth factors, have shown its efficacy in treatment of tennis elbow on a subjective basis only.

Material and methods: We tried to measure the efficacy of locally injected autologous PRP, subjectively by functional oxford elbow score and pain score as well as objectively by ultrasonographic evaluation of the morphologic changes (focal hypoechoic, odema, tendon thickness, fraying, tear, cortical erosion, calcification) in common extensor origin in 30 patients with mean age of 39.3 years of recalcitrant tennis elbow.

Results: The mean pain VAS Score improved from 7.7 before injection to 1.8 at final follow up i.e. after 6 months post injection. The Oxford elbow score improved from a mean of 19.2 prior to treatment to 41.3 after the injection at final follow up. 6 months post injection ultrasonography of the involved elbow showed decrease in focal hypoechoic, decreased edema, and improvement in thickness of the tendon and healing of the tear at the origin site.

Conclusion: This study confirms that local PRP by supplying growth factors helps to enhance the stromal and mesenchymal stem cell proliferation and increases tendon vascularity and prevents angiofibroblastic degeneration and thus improves tendon repair and healing property by releasing growth factors and increasing vascularity, which can be documented by improved tendon morphology.

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References

1. Ahmad Z, Siddiqui N, Malik SS, Abdus-Samee M, Tytherleigh-Strong G, Rushton N. Lateral epicondylitis: a review of pathology and management. Bone Joint J. 2013 Sep;95-B(9):1158-64.

2. Behrens SB, Deren ME, Matson AP, Bruce B, Green A. A review of modern management of lateral epicondylitis. Phys Sports Med. 2012 May;40(2):34-40.

3. Smith RW, Papadopolous E, Mani R, Cawley MI. Abnormal microvascular responses in a lateral epicondylitis. Br J Rheumatol.1994;33(12);1166-68.

4. Harmon K, Drezner J, Rao A. Platelet rich plasma for chronic tendinopathy. Br J Sports Med 2013;47:2.

5. Foster TE, Puskas BL, Mandelbaum BR, Gerhardt MB, Rodeo SA. Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med. 2009 Nov;37(11):2259-72.

6. Everts PA, Overdevest EP, Jakimowicz JJ, Oosterbos CJ, Schönberger JP, Knape JT, Van Zundert A. The use of autologous platelet-leukocyte gels to enhance the healing process in surgery - A review. Surg Endosc. 2007 Nov;21(11):2063-8.

7. Kaux JF, Crielaard JM. Platelet-rich plasma application in the management of chronic tendinopathies. Acta Orthop Belg. 2013 Feb;79(1):10-5.

8. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J sports Med. 2006;34(11);1774-8.

9. Hechtman KS, Uribe JW, Botto-van Demden A, Kiebzak GM. Platelet-rich plasma injection reduces pain in patients with recalcitrant epicondylitis. Orthop. 2011;34:92.

10. Tan X, Ju H, Yan W, et al. Autologous platelet lysate local injections for the treatment of refractory lateral epicondylitis. J Orthop Surg Res. 2016;11:17.

11. Palacio EP, Schiavetti RR, Kanematsu M, Ikeda TM, Mizobuchi RR, Galbiatti JA. Effects of platelet-rich plasma on lateral epicondylitis of the elbow: prospective randomized controlled trial. Revista Brasileira de Ortopedia. 2016;51(1):90-95.

12. Lhee SH, Park JY. Prospective randomized clinical study for the treatment of lateral epicondylitis: comparison among PRP (platelet-rich plasm), prolotherapy, physiotherapy and ESWT. J Shoulder Elb Surg. 2013;22(10);30-31.

13. Ahmad Z, Brooks R, Kang SN, Weaver H, Nunney I, Tytherleigh-Strong G, Rushton N. The effect of platelet-rich plasma on clinical outcomes in lateral epicondylitis. Arthroscopy. 2013;29:1851–1862.

14. Gosens T, Peerbooms JC, van Laar W, den Oudsten BL. Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis: a double-blind randomized controlled trial with 2-year follow-up. Am J Sports Med 2011;39:1200–8.

15. Peerbooms JC, Sluimer J, Bruijn DJ, Gosens T. Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. Am J Sports Med 2010;38:255–62.

16. Krogh TP, Fredberg U, Stengaard-Pedersen K, Christensen R, Jensen P, Ellingsen T. Treatment of lateral epicondylitis with platelet-rich plasma, glucocorticoid, or saline: a randomized, double-blind, placebo-controlled trial. Am J Sports Med 2013;41:625–35.

17. Lebiedziński, R., Synder, M., Buchcic, P. et al. A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis. Int Orthop (SICOT) (2015) 39: 2199.

18. Raeissadat SA, Sedighipour L, Rayegani SM, Bahrami MH, Bayat M, Rahimi R .Effect of Platelet-Rich Plasma (PRP) versus Autologous Whole Blood on Pain and Function Improvement in Tennis Elbow: A Randomized Clinical Trial. Pain Res Treat. 2014;19:52-5.

19. Raeissadat SA, Rayegani SM, Hassanabadi H, Rahimi R, Sedighipour L, Rostami K. Is Platelet-rich plasma superior to whole blood in the management of chronic tennis elbow: one year randomized clinical trial. BMC Sports Sci Med Rehabil. 2014, Mar 18;6:12.

20. Thanasas C, Papadimitriou G, Charalambidis C, Paraskevopoulos I, Papanikolaou A: Platelet-rich plasma versus autologous whole blood for the treatment of chronic lateral elbow epicondylitis. Am J Sports Med. 2011;39: 2130-2134.

21. Creaney L, Wallace A, Curtis M, Connell D. Growth factor-based therapies provide additional benefit beyond physical therapy in resistant elbow tendinopathy: a prospective, single-blind, randomised trial of autologous blood injections versus platelet-rich plasma injections. Br J Sports Med. 2011;45(12):966–971.

22. Rabago D, Best TM, Zgierska AE, Zeisig E, Ryan M, Crane D. A systematic review of four injection therapies for lateral epicondylosis: prolotherapy, polidocanol, whole blood and platelet-rich plasma. Br J Sports Med. 2009;43(7):471–481.

23. Connell D, Burke F, Coombes P, McNealy S, Freeman D, Pryde D, et al. Sonographic examination of lateral epicondylitis. AJR Am J Roentgenol 2001;176:777–82.

24. Levin D, Nazarian LN, Miller TT, O’Kane PL, Feld RI, Parker L, et al. Lateral epicondylitis of the elbow: US findings. Radiology 2005;237:230–4.
Published
2019-06-30
CITATION
DOI: 10.5281/zenodo.3969934
Published: 2019-06-30
How to Cite
1.
Jain S, Banodha L, Kelkar R, Gautam V. Objective Evaluation Of Tendon Morphology By Ultrasonography In Treatment Of Recalcitrant Tennis Elbow By Autologous Platelet Rich Plasma. ojmpc [Internet]. 2019Jun.30 [cited 2024Dec.22];25(1):23-9. Available from: https://ojmpc.com/index.php/ojmpc/article/view/73
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Original Article