Is Caudal Epidural Steroid Injection Effective In Chronic Low Back Pain Due To Multiple Lumbar Disc Prolapse? A Prospective Study
Abstract
Background: Chronic low back pain has multiple aetiologies, and multiple bulged or prolapsed lumbar intervertebral discs are a frequent finding on MRI. Epidural steroid injections are an established mode of conservative management, working by spreading up and down the epidural space and reducing inflammation. We prospectively investigated the caudal method of epidural steroid injections for such patients with MR proven multiple disc bulges.
Material and Methods: A cohort of 38 patients was enrolled in the study from May 2014 to April 2015. We included patients older than 18 years with history of chronic low back pain with or without neurological claudication, with MRI findings of multiple prolapsed lumbar intervertebral discs not responding to conservative management. Patients were evaluated at baseline, three weeks, three months and six months using Objective Parameters of Straight Leg Raise test (SLRT) and Claudication distance and subjective parameters of pain using Numeric Pain Rating Scale (NPRS) and Disability using Oswestry Disability Index (ODI).
Results: The 38 patients (27 male and 11 females) had a mean age of 48.34 years, and their mean duration of back pain was 18.2 months. Mean NPRS and ODI improved from 7.21 and 41.8 at baseline to 4.6 and 26.8 respectively at 6 m. Similarly Mean SLRT and Claudication distance improved from 40.8 degrees and 350 m at baseline to 62.9 degrees and 500 m at 6 months. Change in NPRS, ODI and SLRT were statistically significant.
Conclusion: Caudal epidural injections are an effective modality of treatment in managing chronic low back pain due to multiple lumbar disc bulges. They provide significant pain relief, improvement in functional status and facilitate return to work.
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References
Manchikanti L, Singh V, Cash KA, et al. Preliminary results of a randomized, equivalence trial of flouroscopic caudal epidural injections in managing chronic low back pain: Part 2- Disc herniation and Radiculitis. Pain Physician 2008; 11: 801-15.
Choi YS. Pathophysiology of degenerative disc disease. Asian Spine J. 2009;3:39–44.
Palepu V, Kodigudla M, Goel VK. Biomechanics of disc degeneration. Adv Orthop. 2012;2012:726210.
Modic MT, Ross JS. Lumbar degenerative disk disease. Radiology. 2007;245:43–61.
Goh KJ, Khalifa W, Anslow P, Cadoux HT, Donaghy M. The clinical syndrome associated with lumbar spinal stenosis. European neurology. 2004;52:242–249.
Agency for Healthcare Research and Quality Treatment of degenerative lumbar spinal stenosis: summary. Evidence report/technology assessment number 32. AHRQ publication no 01-E047.
Porter RW. Spinal stenosis and neurogenic claudication. Spine. 1996;21:2046–2052.
Bal S, Celiker R, Palaoglu S, Cila A. F wave studies of neurogenic intermittent claudication in lumbar spinal stenosis. American journal of physical medicine & rehabilitation/Association of Academic Physiatrists. 2006;85:135–140.
Inufusa A, An HS, Lim TH, Hasegawa T, Haughton VM, Nowicki BH. Anatomic changes of the spinal canal and intervertebral foramen associated with flexion-extension movement. Spine.1996;21:2412–2420.
Sanders SH, Harden RN, Benson SE et al. Clinical practice guidelines for chronic non-malignant pain syndrome patients II: An evidence-based approach. J Back Musc Rehabil 1999; 13:47-58.
American Geriatrics Society. The management of chronic pain in older persons: New guidelines from the American Geriatrics Society. J Am Geriatr Soc1998; 46:128-150.
McQuay HJ, Moore RA. Epidural corticosteroids for sciatica. An Evidence-Based Resource for Pain Relief. Oxford University Press, New York,1998, pp 216-218.
Manchikanti L, Singh V, Kloth D et al. Interventional techniques in the management of chronic pain. Part 2.0. Pain Physician 2001; 4:24-96.
Koes BW, Scholten RJPM, Mens JMA et al. Efficacy of epidural steroid injections for low back pain and sciatica: A systematic review of randomized clinical trials. Pain 1995; 63:279-288.
Boswell MV, Trescot AM, Datta S, Schultz DM, Hansen HC, et al. Interventional techniques: evidence based practice guidelines in the management of chronic spinal pain. Pain Physician 2007; 10: 7-111.
Eastwood D, William C, Buchan I. Caudal epidurals:The whoosh test. Anaesthesia 1998; 53: 305-7.
Kobayashi S, Shizu N, Suzuki Y, Asai T, Yoshizawa H. Changes in nerve root motion and intraradicular blood flow during intraoperative straight leg raising test. Spine 2003; 28: 1427-34.
Childs JD, Piva SR, Fritz JM. Responsiveness of the numeric pain rating scale in patients with low back pain. Spine 2005; 30:1331-4.
Goebert HW, Jallo SJ, Gardner WJ et al. Painful radiculopathy treated with epidural injections of procaine and hydrocortisone acetate results in 113 patients. Anesth Analg 1961; 140:130-134.
Wilson-MacDonald J, Burt J, Griffi n D, Glynn C. Epidural steroid injection for nerve root compression: a randomized controlled trial. J Bone Joint Surg Br 2005; 87: 352-5.
Buchner M, Zeifang F, Brocai DRC, Schiltenwolf M. Epidural corticosteroid injection in the conservative management of sciatica. Clin Orthop Relat Res 2000; 375: 149-56.
Sayeh FE, Kenanidis EI, Papasvisiliou KA, Potoupnis ME, Kirkos JM, et al. Efficacy of steroid and nonsteroidal caudal epidural injections for low back pain and sciatica. Spine 2009; 34: 1441-7.
Botwin K, Brown LA, Fishman M et al.Fluoroscopically Guided Caudal Epidural Steroid Injections in Degenerative Lumbar Spinal Stenosis. Pain Physician 2007; 10:547-558
Fairbank, Jeremy CT, Paul B. Oswestry Disability Index. Spine 2000; 25: 2940-52.
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